Following an eventful FA Cup fourth round, the Premier League returns with big matches affecting both ends of the table. Sean Dyche takes charge of his first game as Everton manager, when they face Arsenal in Saturday's early game. Then Tottenham and Manchester City headline matchday 22 on Sunday. Here are our Premier League best bets.
Chelsea, and all their new signings, kick the weekend off on Friday with a west London derby at home to Fulham. The pressure will be on head coach Graham Potter more than ever to deliver results after t he club single-handedly spent more than any other league on players last month. Four of the bottom six clubs are on the road, as they fight for their Premier League survival.
Here are our best Premier League bets for Matchday 22 (odds via DraftKings Sportsbook, FanDuel Sportsbook, and Caesars; pick confidence based on a 1-to-5-star scale).
Check out our Premier League best bets.