The Portland Trail Blazers will face off against the Detroit Pistons at 7 p.m. ET on Wednesday at Little Caesars Arena. Detroit is 2-2 overall and 1-0 at home, while Portland is 1-3 overall and 1-2 on the road. The Pistons are favored by 4-points in the latest Pistons vs. Trail Blazers odds, and the over/under is set at 216 points.'
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