The Purdue Boilermakers enter the season with high expectations, but they start off with a tough Big Ten home battle with the Penn State Nittany Lions on Thursday night at Ross-Ade Stadium. The Boilermakers posted nine victories last season, their most since 2003, and knocked off top-five teams Iowa and Michigan State. Now they kick off with a Nittany Lions team that went 7-6 in 2021 but has beaten the Boilermakers nine straight times.'
Kickoff in West Lafayette, Ind . is set for 8 p.m. ET. Penn State is a 3.5-point favorite in the latest Penn State vs. Purdue odds from Caesars Sportsbook, and the Over/Under for total points is set at 53 (see up-to-date'odds for every game this week on our college football odds page).'
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