Patriots vs Bills Prediction, Odds & Best Prop Bets: NFL, Week 17
Patriots vs Bills Prediction, Odds & Best Prop Bets: NFL, Week 17

The New England Patriots (4-10) visit Highmark Stadium to take on the Buffalo Bills (6-9) on Dec. 31. Kickoff is scheduled for 1:00pm EST in Orchard Park, NY.

The Bills are betting favorites in this Week 17 matchup, with the spread sitting at -12 (-110).

The Patriots vs. Bills Over/Under is 41 total points for the game.

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Patriots vs. Bills Prediction

The winning team model predicts the Bills will win this Week 17 game with 87.7% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Based on recent against-the-spread trends, the model predicts the Bills will cover the spread with 72.2% confidence.


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Best Patriots Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for Patriots players this Week 17 game, looking at profitable historical betting trends:

  • Mac Jones has hit the Completions Over in 10 of his last 12 games (+8.15 Units / 62% ROI)
  • Rhamondre Stevenson has hit the Carries Under in his last 7 games (+7.00 Units / 80% ROI)
  • Mac Jones has hit the Rushing Yards Under in 7 of his last 8 games (+5.75 Units / 57% ROI)
  • DeVante Parker has hit the Receptions Under in his last 5 away games (+5.20 Units / 74% ROI)
  • Rhamondre Stevenson has hit the Longest Reception Under in his last 5 games (+5.00 Units / 74% ROI)

Best Bills Player Prop Best Bets Today

And here are some top NFL player prop bets for Bills players for this matchup, looking at profitable historical betting trends:

  • James Cook has hit the Receiving Yards Under in his last 7 games (+7.00 Units / 74% ROI)
  • Josh Allen has hit the Passing Yards Under in 10 of his last 13 games (+6.20 Units / 36% ROI)
  • Josh Allen has hit the Longest Rush Under in his last 5 games (+5.00 Units / 79% ROI)
  • Josh Allen has hit the Rushing Yards Under in his last 5 games (+5.00 Units / 79% ROI)
  • Gabriel Davis has hit the Longest Reception Over in 7 of his last 9 games at home (+4.85 Units / 49% ROI)

  • The New England Patriots have hit the 4Q Game Total Under in 11 of their last 17 games (+4.10 Units / 21% ROI)
  • The New England Patriots have covered the 3Q Spread in 5 of their last 8 away games (+1.95 Units / 21% ROI)
  • The New England Patriots have hit the 3Q Moneyline in 4 of their last 8 away games (+1.55 Units / 18% ROI)
  • The New England Patriots have hit the 3Q Game Total Over in 5 of their last 8 away games (+1.20 Units / 12% ROI)
  • The New England Patriots have hit the 1H Game Total Over in 5 of their last 10 away games (+0.65 Units / 6% ROI)

  • The Buffalo Bills have hit the 3Q Moneyline in 11 of their last 18 games (+7.05 Units / 22% ROI)
  • The Buffalo Bills have covered the 3Q Spread in 12 of their last 18 games (+5.55 Units / 26% ROI)
  • The Buffalo Bills have covered the 2Q Spread in 12 of their last 18 games (+4.80 Units / 23% ROI)
  • The Buffalo Bills have hit the 2Q Game Total Over in 8 of their last 11 games at home (+4.45 Units / 35% ROI)
  • The Buffalo Bills have covered the 2H Spread in 7 of their last 11 games at home (+2.45 Units / 20% ROI)

Patriots Against the Spread (ATS) Record

Against the spread this NFL season, the Patriots went 4-10 (-6.95 Units / -42.38% ROI).

  • Patriots are 4-11 when betting on the Moneyline for -4.05 Units / -23.28% ROI
  • Patriots are 6-9 when betting the Over for -3.9 Units / -23.64% ROI
  • Patriots are 9-6 when betting the Under for +2.4 Units / ROI

Bills Against the Spread (ATS) Record

Against the spread this NFL season, the Bills went 6-9 (-3.75 Units / -23.08% ROI).

  • Bills are 9-6 when betting on the Moneyline for -4.35 Units / -8.68% ROI
  • Bills are 5-10 when betting the Over for -6 Units / -36.36% ROI
  • Bills are 10-5 when betting the Under for +4.5 Units / 27.27% ROI

New England Patriots: Keys to the Game vs. the Buffalo Bills

The Patriots are winless (0-4) when allowing 100 or more rushing yards this season — worst in NFL; League Avg: .383.

The Patriots are 5-14 (.263) when throwing at least 1 interception since the 2022 season — 8th-worst in NFL. The Bills have intercepted 30 passes since the 2022 season — T-4th-most in NFL.

The Patriots are winless (0-6) when allowing 5 or more explosive passes this season — T-worst in NFL; League Avg: .412.

The Patriots are 1-6 (.143) at home this season — worst in NFL; League Avg: .562.

Buffalo Bills: Keys to the Game vs. the New England Patriots

The Bills are 3-1 (.750) when not forcing a turnover this season — T-best in NFL; League Avg: .270.

The Bills are undefeated (9-0) when allowing an average of less than 5 yards on first down plays since the 2022 season — best in NFL; League Avg: .607.

The Bills are 5-2 (.714) when not forcing a turnover since the 2022 season — best in NFL; League Avg: .266.

  
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