The Carolina Panthers will take on the Detroit Lions at 1 p.m. ET on Saturday at Bank of America Stadium. The Lions have won six of their last seven games, including a 20-17 win over the Jets last week. Detroit is favored by 2.5 points in the latest Panthers vs. Lions odds from Caesars Sportsbook, while the over/under is set at 44.5.'
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Panthers vs. Lions odds, line, spread: Proven model reveals NFL picks, predictions for Week 16, 2022
