The Baltimore Orioles (-150) visit Busch Stadium to take on the St. Louis Cardinals (+125) on Wednesday, May 22, 2024. First pitch is scheduled for 2:15pm EDT in St. Louis, MO.

This season, the Orioles are 29-16 against the spread (ATS), while the Cardinals are 23-24 ATS.

Orioles vs Cardinals Starting Pitchers Today:

• Orioles starting pitcher: John Means 2-0, 3.12 ERA
• Cardinals starting pitcher: Kyle Gibson 3-2, 4.09 ERA

Orioles vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Orioles vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Wednesday‘s MLB game with 58.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.

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We’ve highlighted some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

• Gunnar Henderson has hit the Home Runs Over in 15 of his last 39 games (+37.45 Units / 96% ROI)
• Jorge Mateo has hit the Runs Over in 14 of his last 18 games (+18.35 Units / 102% ROI)
• Gunnar Henderson has hit the RBIs Over in 22 of his last 44 games (+16.20 Units / 37% ROI)
• Anthony Santander has hit the Singles Under in 21 of his last 26 games (+13.15 Units / 34% ROI)
• Ryan O’Hearn has hit the Hits Over in 14 of his last 15 games (+13.00 Units / 39% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

• Alec Burleson has hit the Home Runs Over in 5 of his last 18 games (+23.80 Units / 132% ROI)
• Nolan Arenado has hit the Singles Over in 28 of his last 44 games (+11.85 Units / 25% ROI)
• Nolan Arenado has hit the Hits Over in 33 of his last 44 games (+11.30 Units / 12% ROI)
• Brendan Donovan has hit the Runs Under in 26 of his last 37 games (+10.95 Units / 21% ROI)
• Paul Goldschmidt has hit the Total Bases Under in 28 of his last 44 games (+9.15 Units / 14% ROI)

Orioles Best Bets Today:

• The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 21 of their last 30 games (+11.45 Units / 32% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 20 of their last 30 games (+8.35 Units / 19% ROI)
• The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 17 away games (+5.15 Units / 26% ROI)
• The Baltimore Orioles have hit the Moneyline in 11 of their last 15 away games (+5.10 Units / 27% ROI)
• The Baltimore Orioles have covered the Run Line in 19 of their last 36 games (+4.95 Units / 11% ROI)

Cardinals Best Bets Today:

• The St. Louis Cardinals have hit the Game Total Over in 11 of their last 12 games (+9.80 Units / 73% ROI)
• The St. Louis Cardinals have hit the Team Total Under in 24 of their last 39 games (+7.25 Units / 15% ROI)
• The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 33 games (+5.25 Units / 13% ROI)
• The St. Louis Cardinals have hit the Moneyline in 6 of their last 8 games (+4.10 Units / 45% ROI)
• The St. Louis Cardinals have covered the Run Line in 5 of their last 8 games (+2.60 Units / 25% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 23-22 against the Run Line (+4.8 Units / 9.12% ROI).

• 29-16 when betting on the Moneyline for +4.4 Units / 6.8% ROI
• 23-18 when betting on the total runs Over for +3.35 Units / 6.79% ROI
• 18-23 when betting on the total runs Under for -7.55 Units / -15.19% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 23-24 against the Run Line (-2.95 Units / -4.75% ROI).

• 21-26 when betting on the Moneyline for -8.25 Units / -14.28% ROI
• 22-23 when betting on the total runs Over for -3.6 Units / -6.9% ROI
• 23-22 when betting on the total runs Under for -0.9 Units / -1.75% ROI

Cardinals vs Orioles Home Run Prop Bets Today

Cardinals vs Orioles Total Hits Prop Bets Today

Cardinals vs Orioles RBI Prop Bets Today

Cardinals vs Orioles Strikeout Prop Bets Today

Orioles Starting Pitcher Stats & Trends

Right-handed hitters have a groundball rate of just 17% (5/30) against John Means — lowest in MLB over the last two weeks; League Avg: 43% — first Percentile.

John Means has not allowed a walk in his last 87 PAs against a RHH dating back to September 23rd, 2023 — Jake Irvin has the longest active streak at 92.

John Means’ has 7 strikeouts and no walks — tied for best in MLB K:BB ratio over the last two weeks; League Avg: 3.3 — 100th Percentile.

Right-handed hitters have a groundball rate of just 17% (5/30) against John Means over the last 14 days — 3rd lowest among AL Starters over the last two weeks; League Avg: 41% — fifth Percentile.

Cardinals Starting Pitcher Stats & Trends

Kyle Gibson has a strike rate of just 54% (115/214) with runners in scoring position this season — lowest among qualified SPs in MLB; League Avg: 65% — first Percentile.

Kyle Gibson has a strike rate of just 56% (264/473) vs left-handed batters this season — lowest among qualified SPs in MLB; League Avg: 64% — first Percentile.

Kyle Gibson has thrown at least two strikes in his first three pitches to 36% (19/52) of opposing batters this month (3 games) — lowest among qualified SPs in MLB; League Avg: 66% — 0 Percentile.

Kyle Gibson has a strike rate of just 59% (496/843) this season — lowest among qualified SPs in MLB; League Avg: 65% — first Percentile.

Orioles Keys to the Game vs. the Cardinals

  
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