The No. 21 Notre Dame Fighting Irish take on the No. 19 South Carolina Gamecocks in the 2022 TaxSlayer Gator Bowl at 3:30 p.m. ET on Friday. Notre Dame is favored by two points at Caesars Sportsbook, while the over/under is set at 51 (see up-to-date'odds for every game this week on our college football odds page). Before making any Notre Dame vs. South Carolina picks, you NEED to check out the college football predictions from the SportsLine Projection Model.
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