Notre Dame vs. Michigan State odds, line, spread: Proven model reveals college basketball picks, predictions for Nov. 30, 2022

The Notre Dame Fighting Irish will take on the No. 20 Michigan State Spartans at 9:15 p.m. ET on Wednesday at Purcell Pavilion at the Joyce Center. Notre Dame is looking to bounce back from its first loss of the season, which came in a 63-51 setback at St. Bonaventure last Friday. The Spartans are favored by 2.5 points in the latest Notre Dame vs. Michigan State odds from Caesars Sportsbook, while the over/under is set at 137.'
  
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