iv class=”bodyContent col-lg-9 mb-3″>
Just 17 weeks remain in the 2024-25 NFL regular season. For some fanbases, it may seem a whole lot longer than that.
Our NFL Week 2 predictions will try to navigate the wreckage from the opening weekend. However, it's likely a safe bet to steer clear of the Carolina Panthers and New York Giants for the conceivable future.
The NFL Week 2 odds will make that choice relatively easy.
There wasn't a whole lot of change in the NFL Week 2 odds from last week. Everyone's Super Bowl predictions of the Kansas City Chiefs completing the never-before-seen three-peat also seem to be alive and well.
Mike Spector's Bills vs. Dolphins early picks help set the table for the week to come as he hunts for the best Thursday Night Football odds.
NFL picks & predictions Week 2
- Bills vs. Dolphins ear ly picks
- Bills vs. Dolphins prediction
- Bills vs. Dolphins player props
- Bills vs. Dolphins parlay
- Josh Allen player props
- Tua Tagovailoa player props
- Tyreek Hill player props
- Saints vs. Cowboys player props
- Colts vs. Packers player props
- Jets vs. Titans player props
- Giants vs. Commanders player props
- Marvin Harrison Jr. player props
- Steelers vs. Broncos player props
- Bengals vs. Chiefs prediction
- Bengals vs. Chiefs player props
- Bengals vs. Chiefs parlay
- Travis Kelce player props
- Bears vs. Texans early picks
- Bears vs. Texans prediction
- Bears vs. Texans player props
- Bears vs. Texans parlay
- Caleb Williams player props
- C.J. Stroud player props
- Falcons vs. Eagles early picks
- Falcons vs. Eagles prediction
- Falcons vs. Eagles player props
Don't miss the rest of our Week 2 NFL picks. Listed odds for all games via bet365 unless stated otherwise.
Choose One: $200 or $1,000 in Bonuses
Gambling problem? Call 1-800-GAMBLER
Claim Now
Each product featured on our website has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission. 21+. Gambling can be addictive, please play responsibly
NFL odds for Thursday
- When: Thursday, Sept. 12 – 8:15 p.m. ET
- Where: Hard Rock Stadium, Miami Gardens, Fla.
- How to watch: Prime Video
- Moneyline: Bills +115 | Dolphins -135
- Spread: Bills +2.5 (-110) | Dolphins -2.5 (-110)
- Total: 50 (-110/-110)
NFL odds for Sunday
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: AT&T Stadium, Arlington, Texas
- How to watch: FOX
- Moneyline: Saints +250 | Cowboys -310
- Spread: Saints +6.5 (-105) | Cowboys -6.5 (-115)
- Total: 45.5 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: Ford Field, Detroit
- How to watch: FOX
- Moneyline: Bucaneers +230 | Lions -280
- Spread: Buccaneers +6 (-11) | Lions -6 (-110)
- Total: 50.5 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: Lambeau Field, Green Bay, Wisc.
- How to watch: FOX
- Moneyline: Colts -180 | Packers +150
- Spread: Colts -3.5 (-105) | Packers +3.5 (-115)
- Total: 41 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: Nissan Stadium, Nashville
- How to watch: CBS
- Moneyline: Jets -205 | Titans +170
- Spread: Jets -4 (-110) | Titans +4 (-110)
- Total: 42 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: U.S. Bank Stadium, Minneapolis
- How to watch: CBS
- Moneyline: 49ers -230 | Vikings +190
- Spread: 49ers -5 (-110) | Vikings +5 (-110)
- Total: 45.5 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: Gillette Stadium, Foxborough, Mass.
- Moneyline: Seahawks -185 | Patriots +155
- Spread: Seahawks -3.5 (-110) | Patriots +3.5 (-110)
- Total: 37.5 (-110/-110)
< li>How to watch: FOX
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: Northwest Stadium, Landover, Md.
- How to watch: FOX
- Moneyline: Giants +120 | Commanders -140
- Spread: Giants +2.5 (-110) | Commanders -2.5 (-110)
- Total: 43.5 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: Bank of America Stadium, Charlotte
- How to watch: CBS
- Moneyline: Chargers -290 | Panthers +235
- Spread: Chargers -6.5 (-110) | Panthers +6.5 (-110)
- Total: 39.5 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: EverBank Stadium, Jacksonville
- How to watch: CBS
- Moneyline: Browns +165 | Ja guars -200
- Spread: Browns +4 (-110) | Jaguars -4 (-110)
- Total: 41.5 (-110/-110)
- When: Sunday, Sept. 15 – 1 p.m. ET
- Where: M&T Bank Stadium, Baltimore, Md.
- How to watch: CBS
- Moneyline: Raiders +350 | Ravens -450
- Spread: Raiders +9.5 (-110) | Ravens -9.5 (-110)
- Total: 41.5 (-110/-110)
- When: Sunday, Sept. 15 – 4:05 p.m. ET
- Where: State Farm Stadium, Glendale, Ariz.
- How to watch: FOX
- Moneyline: Rams -110 | Cardinals -110
- Spread: Rams -1 (-105) | Cardinals +1 (-115)
- Total: 50 (-110/-110)
- When: Sunday, Sept. 15 – 4:25 p.m. ET
- Where: Empower Field at Mile High, Denver
- How to watch: CBS
- Moneyline: Steelers -170 | Broncos +145
- Spread: Steelers -3 (-115) | Broncos +3 (-105)
- Total: 37 (-110/-110)
- When: Sunday, Sept. 15 – 4:25 p.m. ET
- Where: GEHA Field at Arrowhead Stadium, Kansas City, Mo.
- How to watch: CBS
- Moneyline: Bengals +205 | Chiefs -250
- Spread: Bengals +6 (-115) | Chiefs -6 (-105)
- Total: 48 (-110/-110)
- When: Sunday, Sept. 15 – 8:20 p.m. ET
- Where: NRG Stadium, Houston
- How to watch: NBC/Peacock
- Moneyline: Bears +245 | Texans -305
- Spread: Bears +6.5 (-105) | Texans -6.5 (-305)
- Total: 46 (-110/-110)
NFL odds for Monday
- When: Monday, Sept. 16 – 8:15 p.m. ET
- Where: Lincoln Financial Field, Philadelphia
- How to watch: ESPN
- Moneyline: Falcons +230 | Eagles -280
- Spread: Falcons +6.5 (-110) | Eagles -6.5 (-110)
- Total: 48 (-110/-110)< /li>
NFL picks roundup: Week 2
- NFL survivor picks
- NFL ATS picks Week 2
- NFL upset picks
- Anytime TD scorer predictions
- First TD scorer predictions
- NFL best bets Week 2
- NFL parlay picks Week 2
- NFL player props Week 2
NFL feature picks
- Comparing your team's Super Bowl odds against Harvard acceptance rate
- NFL power rankings & Super Bowl odds
- NFL rookie QBs and their 2024 OROY odds
- NFL awards odds
- NFL division winners
- 5 under-25 QBs with best NFL MVP odds
- Which of the 5 highest paid NFL players are getting the best MVP odds?
NFL betting odds pages
| Super Bowl Odds | NFL MVP Odds | NFL Offensive Player of the Year Odds |
| NFL Defensive Player of the Year Odds | NFL Offensive Rookie of the Year Odds | NFL Defensive Rookie of the Year Odds |
| NFL Coach of the Year Odds | NFL Comeback Player of the Year Odds | NFL Win Totals Odds |
| NFL Playoff Odds | NFL Draft Odds |
Here are our best NFL betting sites:
- Caesars Promo Code: SBRBONUS1000 | Read our Caesars Review
- BetMGM Bonus Code: SBRBONUS | Read our BetMGM Review
- bet365 Bonus Code: SBRBONUS | Read our bet365 Review
- FanDuel Promo Code | Read our FanDuel Review
- DraftKings Promo Code | Read our DraftKings Review
(21+. Gambling Problem? Call 1-800-GAMBLER)
* Bonuses not applicable in Ontario.
Not intended for use in MA.
Each betting site featured on SBR has been meticulously researched and selected by our team of experts. If you sign up through our links, we may get a commission.
Related pages
- Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)