NFL Week 1 Odds, Picks & Predictions: Giants vs. Titans (2022)
NFL Week 1 Odds, Picks & Predictions: Giants vs. Titans (2022)

Here is my preview and best bet for the 2022 NFL Week 1 game between the Colts and Texans.

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  • Kickoff: Sunday, Sep. 11, 2022, 4:25 pm ET
  • Location: Nissan Stadium
  • TV: FOX

Giants at Titans: Consensus'Lines

  • Spread: Titans -5.5
  • Over/Under: 43.5
  • Moneyline: Titans -250, Giants +200

Giants at Titans: Betting Percentages

  • Spread: Giants – 49% bets, 92% money
  • Over/Under: Over – 61% bets, money data unavailable
  • Moneyline: Titans – 59% bets, 71% money

Giants at Titans: Key Injuries

New York Giants Injuries

  • LG Shane Lemieux (toe, IR)
  • C/G Nick Gates (knee, PUP)
  • G Marcus McKethan (knee, IR)
  • OT Matt Peart (knee, PUP)
  • WR Collin Johnson (Achilles, IR)
  • WR Sterling Shepard (Achilles) – highly questionable
  • TE Daniel Bellinger (concussion) – questionable
  • QB Tyrod Taylor (back) – questionable
  • EDGE Kayvon Thibodeaux (knee) – questionable
  • S Dane Belton (shoulder) – questionable

Houston Texans Injuries

  • EDGE Harold Landry (knee, IR)
  • LB Monty Rice (undisclosed, PUP)

Injury Analysis

The Giants offensive depth is decimated. The line in particular looks rough. The interior has been hollowed out due to the absence of Lemieux (starter), Gates (top C/G backup) and McKethan (rookie third-stringer). On the perimeter, the team is vulnerable without Peart (top swing tackle).

At receiver, Shepard seems unlikely to play in Week 1 because of his season-ending injury last year, and Johnson (a top backup) is out for the year. Bellinger — a Day 3 rookie-turned-starter who filled in this preseason for since-released veteran Ricky Seals-Jones — is uncertain to play because of a head injury.

And Taylor, one of the league’s best backup quarterbacks, is also questionable.

On the defensive side of the ball, Thibodeaux (No. 1 pass rusher) and Belton (No. 3 safety) are both questionable.

The Titans will miss Landry (16 sacks in 18 games last year) and maybe even Rice (No. 3 linebacker).

Giants at Titans: Situational Spots

New York Giants Situation

The Giants have the easiest schedule of any team (based on the market win totals of all their opponents), so they can afford to lose this game, which is one of the toughest they have. After Week 1, the Giants play 4-of-5 at home, and the fifth game is on a neutral field. Then they play the Jaguars and Seahawks (albeit both on the road) before the Week 9 bye.

After that, the Giants kick off the second half of the year with another 4-of-5 stretch at home, which includes games against the Texans, Lions and Commanders. It’s not inconceivable that the Giants could have an 8-5 record entering the final month … even if they lose in Week 1.

Tennessee Titans

As the No. 1 seed in the AFC last year, the Titans have a tough schedule this year — and they have nine games on the road. It helps that play the Jaguars and Texans twice, and most of the NFC East is manageable.

But they also play the Bills, Chiefs, Chargers, Packers, Bengals, Broncos, Cowboys and Colts (twice), all of whom have win totals of 10 at various sportsbooks.

If the Titans can’t get a win at home against the Giants, this is highly unlikely to be an enjoyable season for their fans.

  
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