NFL Week 1 Odds, Picks & Predictions (2022)
NFL Week 1 Odds, Picks & Predictions (2022)

Our staff shares some of their favorite picks of Week 1 of the 2022 NFL season. Let’s take a look at their favorite spreads to bets and over/under total picks for Week 1.

Prop Bet Analyzer: View top rated props and historical prop performance by player >>

Chargers (-3.5) vs. Raiders
We know the Chargers can light up the scoreboard, but they also have the makings of a top-shelf defense. The Raiders’ problematic offensive line figures to have difficulty fending off the impressive Chargers edge-rushing combo of Khalil Mack and Joey Bosa. In four career starts agains t the Raiders, Justin Herbert has averaged 311.3 passing yards and has thrown 10 TD passes and only one interception. The Chargers averaged 29.0 points in those four games. Look for the Chargers to cruise in their home opener.

  
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