The Kansas City Chiefs are home underdogs against the Cincinnati Bengals, while the San Francisco 49ers are underdogs against the Philadelphia Eagles. Can either team pull the upset? Here are our upset NFL picks based on the best NFL odds.
Kansas City quarterback Patrick Mahomes is set to play with a high ankle sprain, and while his injury is concerning, is it really enough to warrant the Chiefs being home underdogs? The Cincinnati Bengals just took care of business against the Buffalo Bills. Their offensive li ne looked great, and their defense was fantastic. But should Mahomes ever be an underdog at home?
Meanwhile, the 49ers opened as 1.5-point underdogs and the line has moved to 2.5. With so much support being shown to the Eagles, it won't be long before this line hits the key number and potentially passes through it. Can the 49ers' number-one scoring defense slow down the Eagles' second-ranked scoring offense?
Here are our best NFL upset picks for Championship Weekend (odds via FanDuel Sportsbook, DraftKings Sportsbook; pick confidence based on a 1-to-5-star scale).