We have a list of the running backs with the most fantasy points going into Week 6 of the NFL season — scroll down prior to setting your fantasy lineup.
RB season fantasy leaders after Week 5
- Alvin Kamara (Saints): 119.2 Total Fantasy Points (23.8 Per Game)
- Derrick Henry (Ravens): 110.1 Total Fantasy Points (22 Per Game)
- Saquon Barkley (Eagles): 98 Total Fantasy Points (24.5 Per Game)
- Kyren Williams (Rams): 97.1 Total Fantasy Points (19.4 Per Game)
- James Cook (Bills): 84.2 Total Fantasy Points (16.8 Per Game)
- Jordan Mason (49ers): 83.2 Total Fantasy Points (16.6 Per Game)
- Chuba Hubbard (Panthers): 80.5 Total Fantasy Points (16.1 Per Game)
- Aaron Jones (Vikings): 78.7 Total Fantasy Points (15.7 Per Game)
- Brian Robinson Jr. (Commanders): 77.3 Total Fantasy Points (15.5 Per Game)
- James Conner (Cardinals): 74.5 Total Fantasy Points (14.9 Per Game)
- Jonathan Taylor (Colts): 72.6 Total Fantasy Points (18.2 Per Game)
- Zach Charbonnet (Seahawks): 72.1 Total Fantasy Points (14.4 Per Game)
- Breece Hall (Jets): 71.5 Total Fantasy Points (14.3 Per Game)
- Jahmyr Gibbs (Lions): 71.1 Total Fantasy Points (17.8 Per Game)
- Devon Achane (Dolphins): 69.9 Total Fantasy Points (14 Per Game)
- David Montgomery (Lions): 69.5 Total Fantasy Points (17.4 Per Game)
- D’Andre Swift (Bears): 68.9 Total Fantasy Points (13.8 Per Game)
- Bijan Robinson (Falcons): 67.6 Total Fantasy Points (13.5 Per Game)
- Kenneth Walker III (Seahawks): 67.1 Total Fantasy Points (22.4 Per Game)
- Zack Moss (Bengals): 66.5 Total Fantasy Points (13.3 Per Game)
- Rhamondre Stevenson (Patriots): 66.3 Total Fantasy Points (13.3 Per Game)
- J.K. Dobbins (Chargers): 60.6 Total Fantasy Points (15.2 Per Game)
- Jerome Ford (Browns): 59.7 Total Fantasy Points (11.9 Per Game)
- Josh Jacobs (Packers): 59.5 Total Fantasy Points (11.9 Per Game)
- Tony Pollard (Titans): 58.3 Total Fantasy Points (14.6 Per Game)
- Travis Etienne (Jaguars): 58.2 Total Fantasy Points (11.6 Per Game)
- Chase Brown (Bengals): 56.9 Total Fantasy Points (11.4 Per Game)
- Rico Dowdle (Cowboys): 55.2 Total Fantasy Points (11 Per Game)
- Alexander Mattison (Raiders): 51.8 Total Fantasy Points (10.4 Per Game)
- Najee Harris (Steelers): 50.9 Total Fantasy Points (10.2 Per Game)
- Justice Hill (Ravens): 49.2 Total Fantasy Points (9.8 Per Game)
- Rachaad White (Buccaneers): 48.4 Total Fantasy Points (9.7 Per Game)
- Devin Singletary (Giants): 47.3 Total Fantasy Points (11.8 Per Game)
- Austin Ekeler (Commanders): 47.1 Total Fantasy Points (11.8 Per Game)
- Javonte Williams (Broncos): 47 Total Fantasy Points (9.4 Per Game)
- Tank Bigsby (Jaguars): 43.1 Total Fantasy Points (8.6 Per Game)
- Braelon Allen (Jets): 41.5 Total Fantasy Points (8.3 Per Game)
- Bucky Irving (Buccaneers): 41.3 Total Fantasy Points (8.3 Per Game)
- Dare Ogunbowale (Texans): 40.5 Total Fantasy Points (8.1 Per Game)
- Antonio Gibson (Patriots): 37.3 Total Fantasy Points (7.5 Per Game)
- Joe Mixon (Texans): 34.8 Total Fantasy Points (17.4 Per Game)
- Tyjae Spears (Titans): 34.3 Total Fantasy Points (8.6 Per Game)
- Roschon Johnson (Bears): 33.3 Total Fantasy Points (11.1 Per Game)
- Isiah Pacheco (Chiefs): 31.9 Total Fantasy Points (16 Per Game)
- Jaleel McLaughlin (Broncos): 31.9 Total Fantasy Points (6.4 Per Game)
- Miles Sanders (Panthers): 31.6 Total Fantasy Points (6.3 Per Game)
- Jeremy McNichols (Commanders): 30.9 Total Fantasy Points (7.7 Per Game)
- Cam Akers (Texans): 30.4 Total Fantasy Points (7.6 Per Game)
- Emanuel Wilson (Packers): 29.4 Total Fantasy Points (5.9 Per Game)
- Kareem Hunt (Chiefs): 29.2 Total Fantasy Points (14.6 Per Game)
Get up to date NFL odds at BetMGM Sportsbook.. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
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Week 6 NFL schedule
- 49ers at Seahawks: Thursday, 8:15 p.m. | TV: Amazon Prime Video | Live Stream: Prime Video
- Jaguars at Bears: Sunday, 9:30 a.m. | TV: NFL Network | Live Stream: Fubo
- Colts at Titans: Sunday, 1:00 p.m. | TV: CBS | Live Stream: Fubo
- Texans at Patriots: Sunday, 1:00 p.m. | TV: CBS | Live Stream: Fubo
- Browns at Eagles: Sunday, 1:00 p.m. | TV: FOX | Live Stream: Fubo
- Buccaneers at Saints: Sunday, 1:00 p.m. | TV: FOX | Live Stream: Fubo
- Cardinals at Packers: Sunday, 1:00 p.m. | TV: FOX | Live Stream: Fubo
- Commanders at Ravens: Sunday, 1:00 p.m. | TV: CBS | Live Stream: Fubo
- Steelers at Raiders: Sunday, 4:05 p.m. | TV: CBS | Live Stream: Fubo
- Chargers at Broncos: Sunday, 4:05 p.m. | TV: CBS | Live Stream: Fubo
- Falcons at Panthers: Sunday, 4:25 p.m. | TV: FOX | Live Stream: Fubo
- Lions at Cowboys: Sunday, 4:25 p.m. | TV: FOX | Live Stream: Fubo
- Bengals at Giants: Sunday, 8:20 p.m. | TV: NBC | Live Stream: Fubo
- Bills at Jets: Monday, 8:15 p.m. | TV: ESPN
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