All but two teams are in action for the NFL's Week 6 with the Sunday slate starting in London, England once again as we round up all of our betting experts' top NFL predictions for Week 6 while looking to get the best of the NFL odds.
The Denver Broncos and Kansas City Chiefs open the NFL's Week 6 with an AFC West rivalry clash on Thursday Night Football. The Chiefs sit second to the San Francisco 49ers in the consensus Super Bowl odds from our best NFL betting sites, while the Broncos are coming off a 10-point loss to Zach Wilson and the New York Jets last week.
Tottenham Hotspur Stadium in London, England plays host to the Baltimore Ravens and Tennessee Titans and their 9:30 a.m. ET start on Sunday morning. The Buffalo Bills host the New York Giants on Sunday Night Football, and Monday Night Football pits the Los Angeles Chargers against the wound-licking Dallas Cowb oys.
The Green Bay Packers and Pittsburgh Steelers are the two teams on byes this week.
Here are our best NFL predictions for Week 6 based on the NFL Week 6 odds.
NFL picks and predictions for Week 6
- Broncos vs. Chiefs (TNF)
- Ravens vs. Titans (London)
- Commanders vs. Falcons
- Vikings vs. Bears
- Seahawks vs. Bengals
- 49ers vs. Browns
- Panthers vs. Dolphins
- Colts vs. Jaguars
- Saints vs. Texans
- Patriots vs. Raiders
- Cardinals vs. Rams
- Eagles vs. Jets
- Lions vs. Buccaneers
- Giants vs. Bills (SNF)
- Cowboys vs. Chargers (MNF)
NFL Week 6 predictions: Thursday
Broncos-Chiefs pick made by Mike Spector
NFL Week 6 predictions: Sunday
NFL Week 6 predictions: Monday
NFL Week 6 expert picks
- Best bets
- Player props
- Survivor picks
- Upset picks
- Touchdown props
- Teaser picks
- Parlay picks
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NFL betting odds pages
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| NFL Defensive Player of the Year Odds | NFL Most Regular Season Rushing Yards Odds | NFL Win Totals Odds |
| NFL Coach of the Year Odds | NFL Most Regular Season Receiving Yards Odds | NFL Draft Odds |
| NFL Offensive Rookie of the Year Odds |
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