Our NFL predictions for Week 5 have you covered for the first shortened week of the season as four teams are on a bye while we look to get the best of the NFL odds.
The NFL's Week 5 opens with the Chicago Bears taking on the Washington Commanders on Thursday Night Football. From there, the Jacksonville Jaguars have remained in London, England to play the Buffalo Bills as Sunday's slate will kick off nice and early at 9:30 a.m. ET once again. The marquee game of the week has the San Francisco 49ers hosting the Dallas Cowboys on Sunday Night Football as a potential NFC Championship preview.
Meanwhile, the Cleveland Browns, Los Angeles Chargers, Seattle Seahawks, and Tampa Bay Buccaneers will all enjoy an early-season bye. Fans of those teams can go ahead and starting looking at the NFL Week 6 odds and lines.
Here are our best NFL predictions for Week 5 based on th e NFL Week 5 odds.
NFL picks and predictions for Week 5
- Chicago Bears vs. Washington Commanders (TNF)
- Jacksonville Jaguars vs. Buffalo Bills (London)
- Houston Texans vs. Atlanta Falcons
- Carolina Panthers vs. Detroit Lions
- Tennessee Titans vs. Indianapolis Colts
- New York Giants vs. Miami Dolphins
- New Orleans Saints vs. New England Patriots
- Baltimore Ravens vs. Pittsburgh Steelers
- Philadelphia Eagles vs. Los Angeles Rams
- Cincinnati Bengals vs. Arizona Cardinals
- New York Jets vs. Denver Broncos
- Kansas City Chiefs vs. Minnesota Vikings
- Dallas Cowboys vs. San Francisco 49ers (SNF)
- Green Bay Packers vs. Las Vegas Raiders (MNF)
NFL Week 5 predictions: Thursday
Bears-Commanders pick made by Mike Spector
NFL Week 5 predictions: Sunday
NFL Week 5 predictions: Monday
NFL Week 5 expert picks
- Best bets
- Player props
- Survivor picks
- Upset picks
- Touchdown props
- Teaser picks
- Parlay picks
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