There's NFL football taking place on Thursday, Friday, Sunday, and Monday of this week as we round up our betting experts' top NFL predictions for Week 12 based on the odds from our best NFL betting sites.
It's Thanksgiving Week and the NFL is celebrating with the annual Thursday tripleheader as well as the first ever Black Friday game before a shorter but intriguing Sunday slate. Marquee matchups on Sunday include the Jacksonville Jaguars visiting the Houston Texans in a key AFC South showdown, and the Buffalo Bills taking on the Philadelphia Eagles.
Be sure to scour the Super Bowl odds ahead of the action in order to get the best price on any lingering long shots.
Check out our best NFL predictions for Week 12 based on the top NFL Week 12 odds and betting lines.
NFL picks and predictions for Week 12
- Packers vs. Lions (Thanksgiving)
- Commanders vs. Cowboys (Thanksgiving)
- 49ers vs. Seahawks (Thanksgiving)
- Dolphins vs. Jets (Black Friday)
- Saints vs. Falcons
- Steelers vs. Bengals
- Panthers vs. Titans
- Buccaneers vs. Colts
- Patriots vs. Giants
- Jaguars vs. Texans
- Browns vs. Broncos
- Rams vs. Cardinals
- Chiefs vs. Raiders
- Bills vs. Eagles
- Ravens vs. Chargers (SNF)
- Bears vs. Vikings (MNF)
NFL predictions Week 12: Thanksgiving
Packers-Lions prediction made by Mike Spector.
Commanders-Cowboys prediction made by Phil Wood.
49ers-Seahawks prediction made by Brenden Schaeffer.
NFL predictions Week 12: Black Friday
Dolphins-Jets prediction made by Mike Spector.
NFL predictions Week 12: Sunday
NFL predictions Week 12: Sunday Night Football
NFL predictions Week 12: Monday Night Football
NFL expert picks Week 12
- Best bets
- Player props
- Upset picks
- Parlay picks
- Anytime touchdown scorer predictions
- First touchdown scorer predictions
NFL betting odds pages
| Super Bowl Odds | NFL Offensive Rookie of the Year Odds | NFL Sacks Leader Odds |
| NFL MVP Odds | NFL Defensive Rookie of the Year Odds | NFL Best Record Odds |
| NFL Playoff Odds | NFL Comeback Player of the Year Odds | NFL Worst Record Odds |
| NFL Offensive Player of the Year Odds | NFL Most Regular Season Passing Yards Odds | NFL Win Totals Odds |
| NFL Defensive Player of the Year Odds | NFL Most Regular Season Rushing Yards Odds | NFL Draft Odds |
| NFL Coach of the Year Odds | NFL Most Regular Season Receiving Yards Odds |
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Related pages
- Best Sports Betting Sites | Best Sportsbook Promos (U.S. only)