NFL Player Prop Bets & Odds Week 2: Best Props This Week

Our NFL player props went 2-3 last week after a late switch on Monday Night Football, but we're looking for a better result with our NFL Week 2 player prop bets and odds.

Our first player prop is targeting an All-Pro running back on a Super Bowl odds contender with a favorable matchup at home against a reeling rushing defense.

Then, our attention turns to the afternoon slate with two quarterbacks – an NFL MVP odds contender and a struggling rookie passer – who are both worth fading on Sunday.

We'll update this article with a Sunday Night Football odds pick as kickoff nears.

NFL player prop bets for Week 2

NFL odds as of Friday and subject to change. Track the NFL scores for the latest line movement and matchup info.

• Derrick Henry Over 69.5 rushing yards (-125 via BetMGM) vs. Raiders ????
• Jo e Burrow Under 34.5 yards longest completion (-115 via BetMGM) at Chiefs ?????
• Bo Nix Over 0.5 interceptions (-120 via bet365) vs. Steelers ????

NFL picks made Friday; odds subject to change. Our NEW NFL player prop odds tool can help you find the best odds on any market across legal sportsbooks in your area!

I bet against Henry last week against a stout Chiefs defense, but he should be salivating at this matchup with another AFC West opponent.

The Raiders were consistently out of position last week against the Chargers, letting running back JK Dobbins break free for gains of 46 and 61 yards – both of which might have been even longer if he wasn't recovering from an Achilles tear.

Unfortunately, for Las Vegas, Henry has made a career out of busting long gains. His volume with the Ravens is still uncertain, but I still think this matchup and game script should favor him clearing this outlier total at BetMGM.

Best odds: -125 via BetMGM | Implied probability: 55.56%

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Burrow has made a habit of slow starts in his NFL career, and it doesn't look like this season will be any exception.

The Bengals quarterback finished with just 121 yards on 24 attempts last week against the Patriots, averaging a measly 5.04 yards per attempt with a long of 32 yards.

Burrow fell below this mark in three of his first four starts last season and seven of 10 starts overall, and his longest pass through Week 2 of the previous season was 24 yards.

Consider, too, that defenses across the league are playing two high safeties at an aggressive rate with the hopes of taking away the deep shot. The Chiefs are among the best at preventing explosives, and I'd be surprised if they let the Bengals get over the top on Sunday.

Best odds: -115 via BetMGM | Implied probability: 53.49%

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It's hard to imagine a tougher start to your NFL career than facing Mike Macdonald and Mike Tomlin in consecutive weeks.

The Seattle Seahawks defense forced Nix into two interceptions in his career debut – neither of which were all that competitive of throws from the No. 12 pick.

I fully expect Tomlin's group to pick off the rookie passer at least once this Sunday after baiting Kirk Cousins into two miscues last week.

I'm surprised to see this wager dealing at just -120 odds via bet365, where a $10 wager would return $8.33 in profit if the Steelers intercept the rookie Nix in Week 2.

Best odds: -120 via bet365 | Implied probability: 54.55%

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