NFL Patriots vs Bills Predictions, Odds, Picks & Best Bets

The New England Patriots will be trying to join the Buffalo Bills in the postseason when the 2 AFC East rivals collide on Sunday afternoon. New England will clinch a playoff spot with a win, while it would need all kinds of help with a loss or tie. Meanwhile, the Bills want to emerge victorious as they position themselves for AFC seeding – which has become incredibly complicated following last week's Monday Night Football cancellation against the Cincinnati Bengals.'

Here are our predictions and best bets for Sunday's showdown in Buffalo.''

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Patriots vs Bills spread, odds & betting line

Point Spread: Patriots +7, Bills -7
Total Points Over/Under: 43.5 points
Money Line Odds: Patriots +265, Bills -320'

  
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