Week 10 of the NFL season got started with a snoozefest between the Bears and Panthers, but Sunday’s slate promises to be a much more exciting day of action. We have the Colts battling the Patriots in Germany at 9:30 am ET to kick us off, before a strong 10 games to carry us through to Sunday Night Football. I’ve already'cashed 2 NFL mega parlays this season at +1457 and +1381 odds, and now I’m looking to secure another one! Let’s dive into my NFL mega parlay for Week 10, but make sure you also ready our NFL picks for every game.
For this parlay, I’m taking 2 underdogs on the money line and another dog on an alternate spread. Let’s break each of them down.
Jacksonville Jaguars ML over San Francisco 49ers (+132)
To start off this NFL mega parlay, we’re taking the Jaguars to pull of the victory against the 49ers. It’s not everyday you get a 6-2 team as a home underdog against a 5-3 team, but that’s what we have here. Public perception remains high on San Francisco following their 3-game skid, but I’m not so sure. There’s no doubting their relentless defense and the ability of star running back Christian McCaffrey, but I have a feeling that the true Brock Purdy is beginning to show himself and I’m not so sure he has what it takes to take the 49ers all the way. Now they’re coming up against a Jacksonville team that is fresh off their bye and has won 5 in a row. Trevor Lawrence is looking red-hot with Calvin Ridley and Christian Kirk at his disposal, while running back Travis Etienne has been a touchdown machine. Give me the Jags to pile more pressure on the 49ers.