The Week 16 NFL schedule coincides with the holidays, with 10 games on Christmas Eve on Saturday and another three on Christmas Day. Several games with major playoff implications will take place, including Texans vs. Browns, in which Houston is favored by 2.5 points in the latest Week 16 NFL odds. Other games and Week 16 NFL spreads to monitor include Colts vs. Falcons (+2), Cowboys vs. Dolphins (-1.5) and Ravens vs. 49ers (-5).
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