New York Giants at New England Patriots odds, picks and prediction

The New York Giants and New England Patriots meet in their preseason opener Thursday. Kickoff from Gillette Stadium is set for 7 p.m. ET (NFL Network). Below, we analyze Tipico Sportsbook’s lines around the Giants vs. Patriots odds, and make our best NFL picks, predictions and bets.

The Giants aren’t likely to play QB Daniel Jones and the starting offense much in this one. He and RB Saquon Barkley have been injury prone, and the weather forecast calls for potential showers and storms with breezy conditions.

The Patriots won all 3 of their preseason games last season, including a visit to the Meadowlands against the Giants. New England should be able to spoil head coach Brian Daboll’s preseason debut.

Giants at Patriots odds

Odds provided by Tipico Sportsbook; access'USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Wednesday at noon ET.

  • Money line (ML): Giants -130 (bet $130 to win $100) | Patriots +105 (bet $100 to win $105)
  • Against the spread (ATS): Giants -2.5 (-108) | Patriots +2.5 (-112)
  • Over/Under (O/U): 33.5 (O: -115 | U: -105)

  
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