New England Patriots at San Francisco 49ers odds picks and predictions
New England Patriots at San Francisco 49ers odds picks and predictions

The New England Patriots (1-2) visit the San Francisco 49ers (1-2) Sunday. Kickoff from Levi’s Stadium is scheduled for 4:05 p.m. ET (FOX). Let’s analyze BetMGM Sportsbook’s NFL odds around the Patriots vs. 49ers odds, and'make our expert NFL picks and predictions.

After winning their first game of the season, the Patriots have dropped 2 straight. They lost 24-3 as 6.5-point underdogs at the New York Jets Sept. 19. QB Jacoby Brissett'went 12 of 18 for 98 yards before getting pulled for QB Drake Maye, who went 4 of 8 for 22 yards. New England had just 78 yards on the ground in the loss.

The 49ers have also dropped back-to-back games after winning their opener. They lost 27-24 as 6.5-point favorites at the LA Rams in Week 3. QB Brock Purdy'went 22 of 30 for 292 yards with 3 touchdowns, all to WR Jauan Jennings'who had 11 receptions for 175 yards.

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Patriots at 49ers odds

  
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