Two of the most historic programs reside in the Big Ten East, with the Michigan Wolverines and the Penn State Nittany Lions. They sit second and seventh all-time in wins, respectively, and have claimed Big Ten titles in the last decade.
They are always among the favorites in college football betting.
Penn State vs. Michigan Series History
Despite being two of college football's blue-bloods, these programs first faced off in 1993. Both programs have had their lulls over the last 10-15 years. Michigan slumped in the Rich Rodriguez and Brady Hoke eras, while Penn State had to dig their way out of the Jerry Sandusky scandal.
Michigan leads the series 15-10, but the teams have split the last 14 matchups dating back to 2007. Michigan broke a two-game losing skid on their way to the Big Ten title last season.