March Madness odds 2023: Who has best, worst odds in East Region to reach Final Four entering second round

The first two days of the 2023 NCAA men's basketball tournament brought chaos, with five double digit seeds winning, including the biggest outright betting upset in tournament history. The East region saw that upset, but somehow managed to avoid any other significant disruption.

No. 16 Fairleigh Dickinson shocked No. 1 Purdue, becoming just the second 16-seed to advance out of the first round. They'll face No. 9 Florida Atlantic in the second, with FAU providing the only other seeded upset in the region. It was somehow all chalk the rest of the way with seeds 2-7 all winning.

The departure of Purdue gives Duke and Tennessee a clear path to the Elite Eight and improves both of their Final Four odds at DraftKings Sportsbook. Heading into the second round, Duke is the region favorite at +300, Marquette follows at +320, and Tennessee and Florida Atlantic follow at +500. Duke may be favored, but this region is wide open with Purdue knocked out.

Here are the odds for each remaining team in the East Region to make it to the Final Four entering the second round of the tournament.

East Region Final Four odds, post first round

Duke: +300
Marquette: +320
Tennessee: +500
Florida Atlantic: +500
Kentucky: +700
Kansas State: +900
Michigan State: +1000
Fairleigh Dickinson: +1400

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