Louisville vs USC Prediction, Odds & Best Prop Bets – Holiday Bowl
Louisville vs USC Prediction, Odds & Best Prop Bets – Holiday Bowl

The Louisville Cardinals (6-7) visit Petco Park to take on the USC Trojans (3-9) on Dec. 27 in San Diego, CA.

Louisville is a betting favorite in Week 18, with the spread sitting at -7.5 (-110).

The Louisville vs. USC Over/Under is 57.5 total points.

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Louisville vs USC Prediction, Holiday Bowl

Based on recent trends, the winning team model predicts Louisville will win this bowl game with 78.0% confidence.

Louisville vs USC Spread Prediction, Holiday Bowl

Based on recent against-the-spread trends, the model predicts Louisville will cover the spread with 54.2% confidence.

Both predictions factor in up-to-date player injuries for both Louisville and USC, plus offensive & defensive matchups, recent games and key player performances this season.


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  • Louisville has hit the 1Q Moneyline in 9 of their last 13 games (+9.25 Units / 36% ROI)
  • Louisville have covered the 1Q Spread in 11 of their last 13 games (+9.05 Units / 59% ROI)
  • Louisville has hit the Moneyline in 10 of their last 13 games (+4.20 Units / 10% ROI)
  • Louisville has hit the 1Q Game Total Under in 9 of their last 13 games (+3.90 Units / 24% ROI)
  • Louisville have covered the 1H Spread in 8 of their last 13 games (+2.35 Units / 16% ROI)

  • USC has hit the Game Total Over in 10 of their last 13 games (+6.70 Units / 47% ROI)
  • USC has hit the 1H Game Total Over in 5 of their last 8 games at home (+2.00 Units / 24% ROI)
  • USC has hit the 1Q Game Total Over in 7 of their last 13 games (+1.50 Units / 10% ROI)

We’ve highlighted some favorite college football player prop bets for Louisville players, looking at profitable historical betting trends:

Best Louisville Player Prop Bets Today

  • Jawhar Jordan has hit the Rushing Yards Under in his last 4 away games (+4.00 Units / 83% ROI)
  • Jamari Thrash has hit the Receiving Yards Under in his last 4 games (+4.00 Units / 82% ROI)
  • Ahmari Huggins-Bruce has hit the Receiving Yards Under in his last 3 games (+3.00 Units / 82% ROI)
  • Jack Plummer has hit the TD Passes Under in 4 of his last 5 away games (+2.50 Units / 33% ROI)
  • Jack Plummer has hit the Passing Yards Over in 3 of his last 4 games (+1.80 Units / 38% ROI)

Top NCAAF player prop bets for USC players, looking at profitable historical betting trends:

Best USC Player Prop Best Bets Today

  • Austin Jones has hit the Rushing Yards Under in his last 4 games (+4.00 Units / 83% ROI)
  • Caleb Williams has hit the Rushing Yards Under in his last 4 games (+4.00 Units / 82% ROI)
  • Tahj Washington has hit the Receiving Yards Over in 4 of his last 5 games (+2.80 Units / 47% ROI)
  • MarShawn Lloyd has hit the Rushing Yards Over in 4 of his last 5 games at home (+2.80 Units / 47% ROI)
  • Brenden Rice has hit the Receiving Yards Over in his last 2 games (+2.00 Units / 82% ROI)

Louisville Against the Spread (ATS) Record

Louisville is 6-6 against the spread this college football season (-0.55 Units / -3.85% ROI).

  • Louisville is 9-3 when betting on the Moneyline for +3.2 Units / 8% ROI
  • Louisville is 7-6 when betting the Over for +0.4 Units / 2.8% ROI
  • Louisville is 6-7 when betting the Under for -1.7 Units / -11.89% ROI

USC Against the Spread (ATS) Record

USC is 3-9 against the spread this college football season (-6.9 Units / -52.27% ROI).

  • USC is 6-5 when betting on the Moneyline for -1.7 Units / -0.27% ROI
  • USC is 9-3 when betting the Over for +5.7 Units / 43.18% ROI
  • USC is 3-9 when betting the Under for -6.9 Units / -52.27% ROI

Louisville is 16-12 (.571) when the opposing team rushes more than 30 times since the 2021 season– 27th-best in FBS; Average: .416

Louisville is 7-3 (.700) when allowing less than 200 passing yards since the 2022 season– tied for 38th-best in FBS; Average: .566

Louisville is 9-5 (.600) when passing for more than 200 yards since the 2022 season– tied for 33rd-best in FBS; Average: .491

Louisville is 8-2 (.800) when forcing at least one fumble since the 2022 season– tied for 12th-best among Power 5 Teams; Average: .575

USC is winless (0-1) when rushing more than 30 times this season– tied for worst among Power 5 Teams; Average: .468

USC is 13-1 (.929) when allowing less than 3 sacks since the 2022 season– 3rd-best in FBS; Average: .549

USC is 2-6 (.222) when losing at least one fumble since the 2022 season– tied for 29th-worst in FBS; Average: .398

USC was 6-1 (.667) when they have committed less than 60 yards in penalties in the 2022 season– tied for 7th-best among Power 5 Teams; Average: .375

USC has gained 3,573 yards on 267 receptions (13.4 YPR) this season — tied for 24th-best among FBS skill players. Louisville’s defense has allowed 12.9 Yards Per Reception this season — tied for 22nd-worst among FBS defenses.

USC has gained 3,573 yards on 267 receptions (13.4 YPR) this season — third-best among Pac-12 skill players. Louisville’s defense has allowed 12.9 Yards Per Reception this season — tied for 22nd-worst among FBS defenses.

  
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