OddsJam's NCAA experts take you through the betting odds, picks and predictions for this college football matchup between Louisville and Syracuse. This game is set to kick off on September 3, 2022. Syracuse is at home for this college football game.
Louisville vs. Syracuse Betting Odds
Louisville visits Syracuse for this NCAA matchup on September 3, 2022. Kickoff for Saturday's game is 8:00 p.m. ET / 5:00 p.m. PT.
Louisville is favored at -170 moneyline odds on DraftKings. Syracuse is +145 underdogs on the moneyline in this matchup vs. Louisville and +3.5 on the point spread at -110 odds.