Louisville vs. Miami odds, line: Advanced computer college football model releases spread pick for Saturday's ACC game
Louisville vs. Miami odds, line: Advanced computer college football model releases spread pick for Saturday's ACC game

The No. 9 Louisville Cardinals can clinch their first appearance in the ACC Championship Game when they face the Miami Hurricanes on Saturday in a conference clash at Hard Rock Stadium outside of Miami. The Cardinals (9-1 overall, 6-1 in ACC) sit in second place in the conference, behind only No. 4 Florida State (10-0, 8-0), which already has clinched a spot in the ACC title game. Louisville needs a win over the Hurricanes (6-4, 2-4) to nail down its spot in the game on Dec. 2 in Charlotte.

Kickoff is scheduled for noon ET. The game is a pick 'em in the latest Louisville vs. Miami odds. The over/under for total points scored is 46.5. (See up-to-date'odds for every game this week on our college football odds page.)

Before you make any Miami vs. Louisville picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.
  
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