The Louisville Cardinals visit Lucas Oil Stadium to take on the Indiana Hoosiers on Sep. 16. Kickoff is scheduled for 12:00pm EDT in Indianapolis.
Louisville is a betting favorite in Week 3, with the spread sitting at -10 (-110).
The Louisville vs. Indiana Over/Under is 52.5 total points.
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Louisville vs Indiana Prediction for Week 3
Based on recent trends, the winning team model predicts Louisville will win this game with 63.4% confidence.
Louisville vs Indiana Spread Prediction for Week 3
Based on recent against-the-spread trends, the model predicts Indiana will cover the spread with 53.3% confidence.
Both predictions factor in up-to-date player injuries for both Louisville and Indiana, plus offensive & defensive matchups, recent games and key player performances this season.
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Louisville Best Bets & Trends for ATS, Moneyline & Totals
- Louisville has hit the 1Q Game Total Under in their last 7 games (+7.00 Units / 82% ROI)
- Louisville has hit the 1H Game Total Under in 7 of their last 8 games (+5.90 Units / 66% ROI)
- Louisville has hit the 1H Moneyline in 6 of their last 11 games (+3.10 Units / 16% ROI)
- Louisville has hit the Team Total Over in 6 of their last 9 games (+2.60 Units / 25% ROI)
- Louisville have covered the Spread in 8 of their last 13 games (+2.50 Units / 17% ROI)
Indiana Best Bets & Trends for ATS, Moneyline & Totals
- Indiana has hit the 1Q Moneyline in their last 4 games (+4.80 Units / 120% ROI)
- Indiana have covered the 1H Spread in 6 of their last 8 games (+3.85 Units / 45% ROI)
- Indiana has hit the 1H Moneyline in 3 of their last 5 games (+3.55 Units / 71% ROI)
- Indiana have covered the 1Q Spread in 5 of their last 7 games (+3.00 Units / 27% ROI)
- Indiana has hit the 1H Game Total Under in 4 of their last 5 games at home (+2.90 Units / 53% ROI)
Best Louisville Player Prop Bets Today
We’ve highlighted some favorite college football player prop bets for Louisville players for Week 3, looking at profitable historical betting trends:
- Ahmari Huggins-Bruce has hit the Receiving Yards Under in 5 of his last 6 games (+3.80 Units / 52% ROI)
Louisville Against the Spread (ATS) Record
Louisville is 1-1 against the spread this college football season (-0.1 Units / -4.55% ROI).
- Louisville is 1-0 when betting on the Moneyline for +1 Units / 33.33% ROI
- Louisville is 2-0 when betting the Over for +2 Units / 90.91% ROI
- Louisville is 0-2 when betting the Under for -2.2 Units / -100% ROI
Indiana Against the Spread (ATS) Record
Indiana is 2-0 against the spread this college football season (+2 Units / 90.91% ROI).
- Indiana is 2-7 when betting on the Moneyline for -2.35 Units / -22.17% ROI
- Indiana is 1-1 when betting the Over for -0.1 Units / -4.55% ROI
- Indiana is 1-1 when betting the Under for -0.1 Units / -4.55% ROI
Louisville is 8-4 (.571) when not losing a fumble since the 2021 season– 15th-best among Power 5 Teams; Average: .423
Louisville is 4-1 (.667) when not losing a fumble since the 2022 season– tied for 7th-best among Power 5 Teams; Average: .398
Louisville is 8-3 (.727) when forcing at least one fumble since the 2021 season– tied for 15th-best among Power 5 Teams; Average: .570
Louisville is undefeated (2-0) when converting more than 50% of third down conversions since the 2021 season– tied for 7th-best among Power 5 Teams; Average: .435
Indiana is 1-15 (.062) when not forcing a fumble since the 2021 season– 2nd-worst among Power 5 Teams; Average: .452
Indiana is 1-10 (.091) when the opposing team commits less than 60 yards in penalties since the 2021 season– tied for 3rd-worst among Power 5 Teams; Average: .513
Indiana is 1-16 (.053) when converting less than 50% of third down conversion opportunities since the 2021 season– 3rd-worst among Power 5 Teams; Average: .356
Indiana is 3-15 (.143) when rushing more than 30 times since the 2021 season– tied for 5th-worst in FBS; Average: .520
Indiana’s TEs has 3 receptions in 2 games (just 1.5 per game) this season — tied for worst among Big Ten TEs. Louisville’s defense has allowed just 13.5 receptions per game this season — third-best among ACC defenses.
Indiana’s TEs has 3 receptions in 2 games (just 1.5 per game) this season — tied for worst among Big Ten TEs. Louisville’s defense has allowed just 13.5 receptions per game this season — tied for 20th-best among FBS defenses.