Michigan State last made the Final Four in 2019. Overall, they have 10 Final Four appearances.
Coach Tom Izzo has 25 NCAA Tournament appearances in 28 seasons as Michigan State head coach. It's the third-longest NCAA Tournament streak of all time'and second-longest active streak.
Michigan State NCAA Tournament History
| Year | NCAA Tournament Result |
| 2021-22 | Lost NCAA Tournament Second Round |
| 2020-21 | Lost NCAA Tournament First Four |
| 2018-19 | Lost NCAA Tournament National Semifinal |
| 2017-18 | Lost NCAA Tournament Second Round |
| 2016-17 | Lost NCAA Tournament Second Round |
| 2015-16 | Lost NCAA Tournament First Round |
| 2014-15 | Lost NCAA Tournament National Semifinal |
| 2013-14 | Lost NCAA Tournament Regional Final |
| 2012-13 | Lost NCAA Tournament Regional Semifinal |
| 2011-12 | Lost NCAA Tournament Regional Semifinal |
| 2010-11 | Lost NCAA Tournament Second Round |
| 2009-10 | Lost NCAA Tournament National Semifinal |
| 2008-09 | Lost NCAA Tournament National Final |
| 2007-08 | Lost NCAA Tournament Regional Semifinal |
| 2006-07 | Lost NCAA Tournament Second Round |
| 2005-06 | Lost NCAA Tournament First Round |
| 2004-05 | Lost NCAA Tournament National Semifinal |
| 2003-04 | Lost NCAA Tournament First Round |
| 2002-03 | Lost NCAA Tournament Regional Final |
| 2001-02 | Lost NCAA Tournament First Round |
| 2000-01 | Lost NCAA Tournament National Semifinal |
| 1999-00 | Won NCAA Tournament National Final |
| 1998-99 | Lost NCAA Tournament National Semifinal |
| 1997-98 | Lost NCAA Tournament Regional Semifinal |
| 1994-95 | Lost NCAA Tournament First Round |
| 1993-94 | Lost NCAA Tournament Second Round |
| 1991-92 | Lost NCAA Tournament Second Round |
| 1990-91 | Los t NCAA Tournament Second Round |
| 1989-90 | Lost NCAA Tournament Regional Semifinal |
| 1985-86 | Lost NCAA Tournament Regional Semifinal |
| 1984-85 | Lost NCAA Tournament First Round |
| 1978-79 | Won NCAA Tournament National Final |
| 1977-78 | Lost NCAA Tournament Regional Final |
| 1958-59 | Lost NCAA Tournament Regional Final |
| 1956-57 | Lost NCAA Tournament National Semifinal |
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