The Chiefs finished 12-5 a season ago and were knocked out of the playoffs in the Conference Championship round. They scored 28.2 points per game (fourth in the league) while conceding 21.4 (eighth). The Cardinals’ 2021 record was 11-6, and they lost in the Wild Card round of the playoffs. They averaged 26.4 points per game on offense (11th in the NFL) while giving up 21.5 per contest on defense (ninth).
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Chiefs vs. Cardinals Betting Information
National Football League odds courtesy of Tipico Sportsbook. Odds updated Monday at 11:31 PM ET. For a full list of sports betting odds, access USA TODAY Sports Betting Scores Odds Hub.
- Spread Favorite: Chiefs (-3.5)
- Moneyline: Chiefs (-177), Cardinals (+149)
- Total: 53 Points
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Recent Chiefs Betting Info
- The Chiefs beat the spread eight times in 17 games last year.
- The Chiefs’ ATS record as 3.5-point favorites or more was 5-8 last season.
- Last season, 10 of the Chiefs’ 17 games went over the point total.
Recent Cardinals Betting Info
- The Cardinals had 10 wins in 17 games against the spread last year.
- Against the spread, as underdogs of 3.5 points or greater, the Cardinals went 4-0 last season.
- Last year, eight of the Cardinals’ 17 games hit the over.
Chiefs Leaders
- Patrick Mahomes II: 4,839 PASS YDS / 284.6 YPG / 66.3% / 37 TD / 13 INT / 66 CAR / 381 RUSH YDS / 2 TD
- Clyde Edwards-Helaire: 119 CAR / 517 YDS / 30.4 YPG / 4 TD / 19 REC / 129 YDS / 7.6 YPG / 2 TD
- Ronald Jones II: 101 CAR / 428 YDS / 25.2 YPG / 4 TD / 10 REC / 64 YDS / 3.8 YPG / 0 TD
- Travis Kelce: 92 REC / 1,125 YDS / 66.2 YPG / 9 TD
- Mecole Hardman: 59 REC / 693 YDS / 40.8 YPG / 2 TD
- Marquez Valdes-Scantling: 26 REC / 430 YDS / 25.3 YPG / 3 TD
- Chris Jones: 27 TKL / 8.0 TFL / 9.0 SACK / 5 PD
- Nick Bolton: 112 TKL / 11.0 TFL / 3 PD
- L’Jarius Sneed: 76 TKL / 7.0 TFL / 1.0 SACK / 2 INT / 8 PD
Cardinals Leaders
- Kyler Murray: 3,787 PASS YDS / 222.8 YPG / 69.2% / 24 TD / 10 INT / 88 CAR / 423 RUSH YDS / 5 TD
- James Conner: 202 CAR / 752 YDS / 44.2 YPG / 15 TD / 37 REC / 375 YDS / 22.1 YPG / 3 TD
- Darrel Williams: 144 CAR / 558 YDS / 32.8 YPG / 6 TD / 47 REC / 452 YDS / 26.6 YPG / 2 TD
- Marquise Brown: 91 REC / 1,008 YDS / 59.3 YPG / 6 TD
- A.J. Green: 54 REC / 848 YDS / 49.9 YPG / 3 TD
- Zach Ertz: 74 REC / 763 YDS / 42.4 YPG / 5 TD
- Markus Golden: 48 TKL / 10.0 TFL / 11.0 SACK / 1 PD
- Jalen Thompson: 120 TKL / 3.0 TFL / 3 INT / 7 PD
- Byron Murphy: 64 TKL / 0.5 SACK / 4 INT / 12 PD