Kansas City Chiefs at Arizona Cardinals odds, picks and predictions
Kansas City Chiefs at Arizona Cardinals odds, picks and predictions

The Kansas City Chiefs kick off their NFL season on the road against the Arizona Cardinals Sunday. Kickoff is 4:25 p.m. ET (CBS) at State Farm Stadium. Below, we analyze Tipico Sportsbook’s lines around the Chiefs vs. Cardinals odds, and make our expert NFL picks and predictions.

The Chiefs bring a slightly new-look offense to 2022 after trading away speedy WR'Tyreek Hill to the Miami Dolphins. They still have TE'Travis Kelce, but have added receivers Marquez Valdes-Scantling'and'JuJu Smith-Schuster. They also lost 2 starting defensive backs in free agency.

The Cardinals inked QB'Kyler Murray'to a huge contract extension this offseason and added WR'Marquise Brown to an already potent group of pass catchers. But they enter Week 1 with questions on defense due to a number of injuries.

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Chiefs at Cardinals odds

  
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