OddsJam's NFL experts take you through the betting odds, picks and predictions for this matchup between the Indianapolis Colts and the Jacksonville Jaguars. This game is set to kick off on September 18, 2022. The Jacksonville Jaguars are at home for this game.
Indianapolis Colts vs. Jacksonville Jaguars Betting Odds
The Indianapolis Colts visit the Jacksonville Jaguars for this NFL matchup on September 18, 2022. Kickoff for Sunday's game is 1:00 p.m. ET / 10:00 a.m. PT.
The Indianapolis Colts are favored at -220 moneyline odds on FanDuel. The Jacksonville Jaguars are +184 underdogs on the moneyline in this matchup vs. the Indianapolis Colts and +4.5 on the point spread at -110 odds.