The Midwest Region of the NCAA bracket already has a bunch of upsets.
Auburn took care of business against Iowa in the 8-9 matchup. Pittsburgh upset Iowa State in the 6-11 matchup. Lastly, Penn State dominated Texas A&M in the 7-10 matchup as the ten-seed.
Houston, Texas, Xavier, Indiana and Miami all survived the first game of the bracket. At the time of writing this, the region still has its five best teams, unlike most of the other regions.
That will change on Day 2, Round 2.