Houston Astros at San Diego Padres odds, picks and predictions
Houston Astros at San Diego Padres odds, picks and predictions

The Houston Astros (82-69) and San Diego Padres (86-66) meet Wednesday for the finale of a 3-game series. First pitch from Petco Park is set for 6:40 p.m. ET.'Let’s analyze BetMGM Sportsbook’s'MLB odds around the Astros vs. Padres odds and make our expert MLB picks and predictions for the best bets.

Season series: Tied 1-1

Houston escaped with a 4-3 win in 10 innings over San Diego Tuesday as a +108 road underdog. After 2B Jose Altuve'was ejected in the 9th for taking his shoe off — he was pleading his case that he had fouled a ball off his foot — his replacement Grae Kessinger'scored on a 10th-inning, go-ahead RBI single from RF Kyle Tucker.

The loss ended a 4-game win streak for the Padres. San Diego and Houston are essentially playoff locks at this point; their chances of making the postseason are 99.5 and 98.9 percent, respectively, according to FanGraphs.com.

Astros at Padres projected starters

  
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