Houston Astros at Milwaukee Brewers odds and predictions

The Houston Astros (28-20) and the Milwaukee Brewers (26-22) wrap up a 3-game interleague series Wednesday at American Family Field. First pitch is scheduled for 1:10 p.m. ET (MLB Network). Let’s analyze BetMGM Sportsbook’s lines around the Astros vs. Brewers odds and make our expert MLB picks and predictions for the best bets.

Season series: Series tied 1-1

The Astros’ 8-game win streak came to a crashing halt Tuesday as the Brewers posted a 6-0 victory behind RHP Colin Rea. The Astros were held to just 5 hits, and they were shut out for the 1st time since a 2-0 loss at home against the San Francisco Giants on May 2. Houston had won the series opener 12-2 on Monday.

The Brewers bounced back from the 10-run drubbing for their 1st shutout win since a 1-0 victory on April 16 at the San Diego Padres. Milwaukee is now 12-8 in interleague play, the most wins in interleague play by any team in the majors.

Astros at Brewers projected starters

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