Since the NCAA Tournament began seeding teams in 1979, there have been three Final Fours without a No. 1 seed: 1980, 2006, and 2011.
1980 Final Four
The 48-team 1980 NCAA Tournament ended with the Final Four at Market Square Arena in Indianapolis.
- No. 5 Iowa vs. No. 2 Louisville
- No. 6 Purdue vs. 8 UCLA
Louisville beat UCLA in the title game. Had the Bruins won, they would’ve been the lowest seed to win the national championship.
2006 Final Four
The 65-team 2006 tournament ended with the Final Four at the RCA Dome in Indianapolis.
- No. 4 LSU vs. No. 2 UCLA
- No. 3 Florida vs. No. 11 George Mason