The Cleveland Guardians (+140) visit PETCO Park to take on the San Diego Padres (-165) on Wednesday, August 24, 2022. First pitch is scheduled for 4:10pm EDT in San Diego.

The Padres are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+125).

The Guardians vs Padres Over/Under is 7.5 total runs for the game.

So far this season, the Guardians are 65-55 against the spread (ATS), while the Padres are 56-66 ATS.

Guardians vs. Padres Odds, Run Line, Over/Under & Moneyline

Guardians vs Padres Prediction for Today's Game

Based on recent trends the model predicts the Guardians will win Wednesday's matchup with 53.7% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Guardians and Padres and up-to-date player injuries.

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Best Guardians Player Prop Bets Today

We've highlighted some favorite MLB player prop bets for Guardians players for Wednesday's game, looking at profitable historical betting trends:

• Myles Straw has hit the Hits Under in 13 of his last 17 games (+13.95 Units / 82% ROI)
• Josh Naylor has hit the Runs Under in 15 of his last 16 games (+13.30 Units / 49% ROI)
• Steven Kwan has hit the Total Bases Over in 24 of his last 41 games (+13.20 Units / 32% ROI)
• Oscar Gonzalez has hit the Hits Over in 14 of his last 17 games (+12.30 Units / 39% ROI)
• Myles Straw has hit the Total Bases Under in 11 of his last 12 games (+12.25 Units / 70% ROI)

Best Padres Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Padres players for Wednesday's game, looking at profitable historical betting trends:

• Josh Bell has hit the Singles Under in 30 of his last 43 games (+15.55 Units / 30% ROI)
• Ha-Seong Kim has hit the Hits Over in 37 of his last 52 games (+15.40 Units / 18% ROI)
• Ha-Seong Kim has hit the Singles Over in 30 of his last 51 games (+14.00 Units / 27% ROI)
• Josh Bell has hit the RBIs Under in 41 of his last 54 games (+13.95 Units / 12% ROI)
• Josh Bell has hit the Hits Under in 17 of his last 28 games (+13.70 Units / 40% ROI)

Padres vs Guardians Home Run Prop Bets Today

Padres vs Guardians Total Hits Prop Bets Today

Padres vs Guardians RBI Prop Bets Today

Padres vs Guardians Strikeout Prop Bets Today

Positive Betting Trends for the Guardians Run Line, Moneyline, Run Totals

• The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 17 of their last 21 away games (+13.20 Units / 53% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 11 of their last 13 away games (+11.30 Units / 73% ROI)
• The Cleveland Guardians have hit the Moneyline in 29 of their last 51 away games (+11.30 Units / 19% ROI)
• The Cleveland Guardians have covered the Run Line in 25 of their last 41 away games (+7.15 Units / 13% ROI)
• The Cleveland Guardians have hit the 1st Five Innings (F5) Total Over in 33 of their last 62 away games (+6.45 Units / 9% ROI)

Positive Betting Trends for the Padres: Run Line, Moneyline, Run Totals

• The San Diego Padres have hit the 1st Five Innings (F5) Total Under in 56 of their last 100 games (+15.85 Units / 15% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this MLB season, the Guardians have gone 65-55 against the Run Line (+5.55 Units / 3.65% ROI).

• 65-55 when betting on the Moneyline for +11.3 Units / 7.58% ROI
• 55-57 when betting on the total runs Over for -7.55 Units / -5.72% ROI
• 57-55 when betting on the total runs Under for -3.4 Units / -2.57% ROI

Padres Against the Spread (ATS) Record

Against the spread this MLB season, the Guardians have gone 56-66 against the Run Line (-13.2 Units / -8.74% ROI).

• 66-56 when betting on the Moneyline for -10.25 Units / -5.68% ROI
• 57-62 when betting on the total runs Over for -10.35 Units / -7.78% ROI
• 62-57 when betting on the total runs Under for -1.2 Units / -0.88% ROI

Cal Quantrill: Guardians Starting Pitcher Stats & Trends

Right-handed hitters have a miss rate of just 15% (92/598) against Cal Quantrill this season – lowest among qualified SPs in MLB; League Avg: 26% – first Percentile.

Cal Quantrill has a strikeout rate of just 31% (88 SO in 282 PAs) with two-strikes this season – 2nd lowest among qualified SPs in MLB; League Avg: 43% – third Percentile.

Opponents have a miss rate of just 19% (32/172) against Cal Quantrill on the first pitch of at-bats this season – 4th lowest among qualified SPs in MLB; League Avg: 26% – seventh Percentile.

Opponents have a two strike miss rate of just 17% (63/363) against Cal Quantrill this season – 4th lowest among qualified SPs in MLB; League Avg: 25% – seventh Percentile.

Blake Snell: Padres Starting Pitcher Stats & Trends

Blake Snell has walked 90 of 721 right-handed batters (12%) since the start of last season – highest in MLB among starting pitchers with at least 141 total IP; League Avg: 7% – 0 Percentile.

Opponents have a groundball batting average of .358 (29 GB hits out of 81 GBs) against Blake Snell this season – 2nd highest in MLB among starting pitchers with at least 60 total IP; League Avg: .233 – first Percentile.

Blake Snell has walked 43 of 242 batters (18%) with runners in scoring position since the start of last season – highest in MLB among starting pitchers with at least 141 total IP; League Avg: 9% – 0 Percentile.

Blake Snell has a strikeout rate of 57% (60 SO in 106 PAs) on low non-fastballs this season – 2nd best in MLB among starting pitchers with at least 60 total IP; League Avg: 33% – 99th Percentile.

Guardians Keys to the Game vs. the Padres

  
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