Guardians vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Sep. 22
Guardians vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Sep. 22

The Cleveland Guardians (-110) visit Busch Stadium to take on the St. Louis Cardinals (-110) on Sunday, September 22, 2024. First pitch is scheduled for 2:15pm EDT in St. Louis, MO.

This season, the Guardians are against the spread (ATS), while the Cardinals are ATS.

Guardians vs Cardinals Starting Pitchers Today:

  • Guardians starting pitcher: Gavin Williams 3-10, 5.10 ERA
  • Cardinals starting pitcher: Andre Pallante 7-8, 3.85 ERA

Guardians vs. Cardinals Odds, Run Line, Over/Under & Moneyline

Guardians vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Sunday‘s MLB game with 51.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Sunday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Lane Thomas has hit the Home Runs Over in 6 of his last 18 games (+21.40 Units / 119% ROI)
  • Josh Naylor has hit the Hits Under in 10 of his last 14 away games (+10.90 Units / 63% ROI)
  • Jose Ramirez has hit the RBIs Under in 19 of his last 24 games (+9.70 Units / 23% ROI)
  • Josh Naylor has hit the Singles Under in 29 of his last 45 games (+9.45 Units / 17% ROI)
  • Andres Gimenez has hit the Runs Under in 19 of his last 25 away games (+9.30 Units / 21% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Sunday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Masyn Winn has hit the Home Runs Over in 5 of his last 21 games at home (+24.50 Units / 117% ROI)
  • Jordan Walker has hit the Singles Under in 18 of his last 23 games (+11.10 Units / 34% ROI)
  • Nolan Arenado has hit the Hits Over in 36 of his last 48 games (+10.80 Units / 10% ROI)
  • Masyn Winn has hit the Total Bases Over in 15 of his last 24 games at home (+10.45 Units / 42% ROI)
  • Paul Goldschmidt has hit the RBIs Under in 13 of his last 15 games (+9.00 Units / 27% ROI)

  • The Cleveland Guardians have hit the Game Total Under in 43 of their last 72 away games (+16.80 Units / 21% ROI)
  • The Cleveland Guardians have hit the Moneyline in 90 of their last 155 games (+13.82 Units / 7% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 29 of their last 43 away games (+13.70 Units / 28% ROI)
  • The Cleveland Guardians have covered the Run Line in 17 of their last 27 games (+9.05 Units / 26% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 7 of their last 8 games (+6.05 Units / 56% ROI)

  • The St. Louis Cardinals have hit the Game Total Under in 17 of their last 25 games at home (+9.20 Units / 34% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 14 games (+8.05 Units / 46% ROI)
  • The St. Louis Cardinals have covered the Run Line in 20 of their last 33 games (+4.70 Units / 10% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 16 of their last 29 games (+4.60 Units / 14% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Cardinals vs Guardians Home Run Prop Bets Today

Over Under

Paul Goldschmidt (STL)
0.5 +550 0.5 -800

Jose Ramirez (CLE)
0.5 +600 0.5 -900

Kyle Manzardo (CLE)
0.5 +650 0.5 -1000

Jordan Walker (STL)
0.5 +650 0.5 -1000

Alec Burleson (STL)
0.5 +675 0.5 -1100

Cardinals vs Guardians Total Hits Prop Bets Today

Over Under

Masyn Winn (STL)
0.5 -250 0.5 +175

Alec Burleson (STL)
0.5 -250 0.5 +175

Jose Ramirez (CLE)
0.5 -225 0.5 +170

Will Brennan (CLE)
0.5 -200 0.5 +150

Lane Thomas (CLE)
0.5 -200 0.5 +150

Cardinals vs Guardians RBI Prop Bets Today

Over Under

Josh Naylor (CLE)
0.5 +170 0.5 -225

Jose Ramirez (CLE)
0.5 +185 0.5 -250

Lane Thomas (CLE)
0.5 +190 0.5 -250

Paul Goldschmidt (STL)
0.5 +200 0.5 -275

Nolan Arenado (STL)
0.5 +210 0.5 -275

Cardinals vs Guardians Strikeout Prop Bets Today

Over Under

Gavin Williams (CLE)
5.5 +120 5.5 -160

Andre Pallante (STL)
4.5 +125 4.5 -165

20 of Gavin Williams’ 71 breaking pitch strikeouts (28%) have been backdoor since last season — 4th highest in MLB among starting pitchers with at least 126 total IP; League Avg: 14% — 96th Percentile.

10 of Gavin Williams’ 31 breaking pitch strikeouts (32%) have been backdoor this season — 5th highest in MLB among starting pitchers with at least 61 total IP; League Avg: 14% — 96th Percentile.

Left-handed hitters have a groundball rate of just 29% (6/21) against Gavin Williams this month (4 games) — 5th lowest among qualified SPs in MLB; League Avg: 41% — eighth Percentile.

Gavin Williams has struck out just 15% (6/40) of right-handed batters he faced this month (4 games) — 6th lowest among qualified SPs in MLB; League Avg: 24% — eighth Percentile.

Cardinals Starting Pitcher Stats & Trends

Opponents have a groundball rate of 68% (131/194) against Andre Pallante in two-strike counts since last season — highest in MLB among starting pitchers with at least 126 total IP; League Avg: 45% — 100th Percentile.

Opponents have a groundball rate of 68% (246/363) against Andre Pallante in non-two strike counts since last season — highest in MLB among starting pitchers with at least 126 total IP; League Avg: 42% — 100th Percentile.

Left-handed hitters have a groundball rate of 76% (216/284) against Andre Pallante since last season — highest in MLB among starting pitchers with at least 126 total IP; League Avg: 42% — 100th Percentile.

Opposing hitters have a groundball rate of 66% (91/139) against Andre Pallante when he’s behind in the count since last season — highest in MLB among starting pitchers with at least 126 total IP; League Avg: 40% — 100th Percentile.

Guardians Keys to the Game vs. the Cardinals

  
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