USC takes a break from Pac-12 play for one week to host Fresno State. We're breaking down the betting angles with our Fresno State-USC picks.
The USC Trojans avenged a 42-28 home loss to Stanford last year in a big way during Week 2 with an almost identical 41-28 road victory. The win was the Trojans' 33rd over their previous 52 conference openers, and they're now 24-13 across the school's last 37 such games.
The Trojans bring their high-flying offense home to face a 1 -1 Fresno State team that's looking to avoid a second straight loss to a Pac-12 squad. After defeating Cal Poly 35-7 in their season opener, the Bulldogs lost 35-32 at home to Oregon State as one-point favorites.
Here are our top picks for the college football Week 3 game between Fresno State and USC (odds via PointsBet, BetMGM, and DraftKings Sportsbook; pick confidence is based on a 1-to-5-star scale).