First look: USC vs. Michigan odds and lines
First look: USC vs. Michigan odds and lines

The No. 12 USC Trojans (2-0) travel to Ann Arbor to face the 17th-ranked Michigan Wolverines (2-1) at Michigan Stadium Saturday. Kickoff for this Big Ten opener for both programs is at 3:30 p.m. ET (CBS). Below, we look at USC vs. Michigan odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

The Trojans, who just enjoyed a bye week, are off to a strong start — both on the field and for bettors. They opened with a 27-20 win over LSU on a neutral field in Las Vegas, covering the spread as 4-point underdogs as the Under (66) cashed. They followed with a 48-0 shutout of Utah State as 31-point home favorites — the Under (64) hit in this one, too. The RB duo of Woody Marks and Quinten Joyner combined for 187 yards and 3 TDs vs. Utah State. The Trojans will look to keep the momentum going on this trip to Ann Arbor — their 1st Big Ten game since joining the conference.

Michigan is off to a bumpy start. Following'a tough 31-12 home loss to now-No. 1 Texas, the Wolverines bounced back with a 28-18 win over Arkansas State Saturday. They didn't cover the 21.5-point spread and Under (45.5) hit. The Wolverines led 28-3 before allowing 15 fourth-quarter points. QB Davis Warren completed 11 of 14 passes for 122 yards but with no TDs and 3 interceptions. A bright spot was the RB duo of Kalel Mullings and Donovan Edwards, who combined for 235 yards and 3 touchdowns.

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