First look: San Francisco 49ers at Denver Broncos odds and lines

The San Francisco 49ers (1-1) travel to square off with the Denver Broncos (1-1) on Sunday Night Football in Week 3. Kickoff from Empower Field at Mile High is set for 8:20 p.m. ET (NBC). Below, we look at 49ers vs. Broncos odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The 49ers were able to secure their first win of the season in Week 2 with a 27-7 blowout victory over the Seattle Seahawks following an ugly loss to the Chicago Bears in Week 1. QB Trey Lance suffered a season-ending ankle injury in Week 2, so QB Jimmy Garoppolo will operate San Francisco’s offense again moving forward.

Also see:'All Week 3 odds and lines

The Broncos were able to escape with a narrow 16-9 win over the Houston Texans in Week 2 after being upset by the Seahawks in the season opener. It has been a shaky start for QB Russell Wilson, who completed only 14-of-31 attempts for 219 yards, 1 touchdown and 1 interception in the win against the Texans.

  
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