The San Francisco 49ers and'the Chicago Bears meet in Week 1 action with kickoff from Soldier Field on Sunday, Sept. 11, set for 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook’s lines around the 49ers vs. Bears odds and lines; check back for our NFL picks and predictions.
A new era is set to officially begin for the visiting 49ers as last year’s 3rd-overall draft pick, Trey Lance, is set to take over at quarterback. San Francisco enters the season with lofty expectations and with the 2nd-best odds to win the NFC West behind only the defending champion Los Angeles Rams.
San Francisco finished the preseason 2-1 after falling 17-0 at the Houston Texans in their final appearance. Lance led 3 scoreless drives.
Also see: All Week 1 odds and lines