The San Francisco 49ers (2-2) travel to meet the Carolina Panthers (1-3) Sunday at Bank of America Stadium. Kickoff from Charlotte is scheduled for 4:05 p.m. ET (CBS). Below, we look at 49ers vs. Panthers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.
The 49ers roughed up the defending champs, winning 24-9 against the visiting Los Angeles Rams Monday night behind a strong defensive effort. San Francisco’s defense recorded 7 sacks and posted a pick-6 by 2nd-year DB Talanoa Hufanga.
The Panthers were on the short end of a 26-16 setback at home against the Arizona Cardinals in Week 4, falling to 1-2 straight up and against the spread (SU/ATS) in 3 home games. QB Baker Mayfield is on the hot seat after an ice-cold start with his new team, posting just 4 TD passes and 1 TD run across the first 4 outings.
Also see:'All Week 5 odds and lines