The San Francisco 49ers (10-3) are on the road in Week 15 to face the Arizona Cardinals (3-10) for the 2nd time this season. Kickoff is Sunday at 4:05 p.m. ET at State Farm Stadium (CBS). Below, we look at 49ers vs. Cardinals odds from BetMGM Sportsbook. : SportsbookWire’s NFL picks and predictions.
The 49ers took over the No. 1 seed in the NFC over the weekend. They beat the Seattle Seahawks 28-16 at home, but failed to cover the 16.5-point spread as favorites. It was their 5th consecutive win.
The Cardinals were on their bye in Week 14. They picked up their 3rd win of the season in Week 13 with a 24-10 road win over the Pittsburgh Steelers as 6-point underdogs. It was their 1st road win since Week 10 of 2022.
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