First look: Ole Miss at South Carolina odds and lines
First look: Ole Miss at South Carolina odds and lines

The Ole Miss Rebels (4-1, 0-1 SEC) meet the South Carolina Gamecocks (3-1, 1-1) in Columbia Saturday. Kickoff at Williams-Brice Stadium is set for 3:30 p.m. ET (ESPN). Below, we look at Ole Miss vs. South Carolina odds'from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

Mississippi dropped from 5th to No. 11 in the following Saturday’s 20-17 home loss as a 15.5-point favorite to unranked Kentucky. It was only Ole Miss’ 2nd defeat since Sept. 30,' 2023. The Rebels led the Wildcats 17-13 with 10 seconds to go in the 3rd quarter, but they didn’t score again, and UK manufactured a 6-play, 83-yard drive for the eventual winning touchdown with 2:25 remaining. The Rebels were undone by the Wildcats controlling the football for 39 minutes and 43 seconds, while Ole Miss’ time of possession was 20 minutes and 17 seconds.

South Carolina should be rested after enjoying a bye week. The Gamecocks likely needed it as they’re set to open a tough stretch of their schedule with consecutive games against Ole Miss, No. 2 Alabama, No. 17 Oklahoma and No. 21 Texas A&M. The Gamecocks defeated Akron 50-7 as 24.5-point home favorites in their last outing (Sept. 21).

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