First look: Michigan State vs. Oregon odds and lines
First look: Michigan State vs. Oregon odds and lines

The Michigan State Spartans (3-2, 1-1 Big Ten) and the No. 6 Oregon Ducks (4-0) meet at Autzen Stadium Friday. Kickoff is slated for 9 p.m. ET (FOX). Below, we look at Michigan State vs. Oregon odds from BetMGM Sportsbook’s college football odds before making our expert college football picks and predictions later in the week.

Michigan State dropped their Big Ten home opener to 3rd-ranked Ohio State Saturday, losing 38-7. The Spartans failed to cover as 23.5-point underdogs with the Under (48.5) cashing. Michigan State’s offense struggled, turning the ball over 3 times and finishing with 246 total yards (199 passing, 47 rushing), while the'defense allowed 483 yards (298, 185).

Oregon remained undefeated with a 34-13 victory at UCLA in their Big Ten opener. However, the Ducks didn't cover as 23.5-point underdogs and as' the Under (54.5) hit. QB Dillon Gabriel led the way with 278 passing yards, 3 TDs and an interception, with WR Tez Johnson accounting for 121 yards and 2 scores. The Ducks defense was dominant, limiting UCLA to just 172 total yards (125 passing, 47 rushing).

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