First look: Kansas City Chiefs at San Francisco 49ers odds and lines
First look: Kansas City Chiefs at San Francisco 49ers odds and lines

The Kansas City Chiefs (4-2) head to Levi’s Stadium Sunday to face the San Francisco 49ers (3-3) with kickoff scheduled for 4:25 p.m. ET (FOX). Below, we look at Chiefs vs. 49ers odds from Tipico Sportsbook; check back for all our NFL picks and predictions.

The Chiefs are coming off a close Week 6 loss to the Buffalo Bills. QB Patrick Mahomes boosted his stats with 338 yards passing and 2 TDs, but also had 2 INTs including one to close the game. Mahomes’ favorite target was WR JuJu Smith-Schuster, who had his first 100-yard game (113 total) and first TD of the season. Despite the loss, the Chiefs still narrowly lead the league in points scored per game with 29.8.

The Niners suffered a slightly surprising loss to the Atlanta Falcons last week, allowing QB Marcus Mariota to rack up 3 total TDs. San Francisco couldn’t get its running game going with only 50 yards rushing, while QB Jimmy Garoppolo had 2 INTs on the day. The Falcons’ 28 points was the highest amount allowed by the Niners’ defense this season, though the 49ers still boast the league’s 2nd-best points allowed per game at 14.8.

Also see:'All Week 7 odds and lines

  
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