First look: Indianapolis Colts at Houston Texans odds and lines
First look: Indianapolis Colts at Houston Texans odds and lines

The Indianapolis Colts and Houston Texans meet in a Week 1 opener at NRG Stadium. Their Sept. 11 game will kick off at 1 p.m. (CBS). Below, we analyze Tipico Sportsbook’s lines around the Colts vs. Texans odds and lines; check back for our NFL picks and predictions.

The Colts last year went 6-1 from Nov. 4-Dec. 25, and they were 9-6 heading into the season’s final fortnight. But Indianapolis lost its final 2 games and missed the playoffs. The 2021 Colts' rushing game (149.4 yards per game) ranked 2nd in the NFL.

The Texans struggled mightily in running the football (83.6 YPG, 32nd) en route to logging a 4-13 mark last season. Houston was tabbed as an underdog in 16 of its 17 games.

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Colts at Texans odds, spread and lines

  
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