The Duke Blue Devils (5-2, 2-1 ACC) meet the Louisville Cardinals (6-1, 3-1) on Saturday at Cardinal Stadium in Louisville, Ky. Kickoff is scheduled for 3:30 p.m. ET (ESPN). Below, we look at Duke vs. Louisville odds from FanDuel Sportsbook. : SportsbookWire’s college football picks and predictions.
The Blue Devils held a surprising 20-17 lead at halftime of their game at Florida State on Saturday, but the Seminoles outscored Duke 21-0 in the final 15 minutes for the 38-20 win. Duke failed to cover the 13.5-point number as the Over (49) cashed. After a 4-0 straight up (SU) and 3-1 against the spread (ATS) start, the Blue Devils are 1-2 SU/ATS in the past 3 games.
The Cardinals have been stewing for 2 weeks after a stunning loss at Pittsburgh as a 7-point favorite, falling 38-21. That snapped a 6-game win streak to start the season, including a signature win over Notre Dame on Oct. 7. The Cards are both 3-3-1 ATS and OU so far this season.
Duke is No. 21 and Louisville is No. 18 in the US LBM Coaches Poll powered by USA TODAY Sports.