Duke vs. Louisville CFB Prediction and Odds – October 28, 2023
Duke vs. Louisville CFB Prediction and Odds – October 28, 2023

Louisville and Duke meet in College Football action at L&N Federal Credit Union Stadium on Saturday, with kickoff at 3:30PM ET.

Dimers' prediction for Saturday's Duke vs. Louisville game, as well as the latest odds and our in-depth game preview, are featured below.

Today's Duke vs. Louisville prediction is proudly sponsored by Bet365, which has a tasty Bet $5, Get $150 in Bonus Bets offer for new users.

Who Will Win: Duke vs. Louisville

Using cutting-edge computer power and data, Dimers.com has simulated the outcome of Duke vs. Louisville 10,000 times.

Dimers' independent predictive analytics model, DimersBOT, currently gives Louisville a 62% chance of defeating Duke.

More: Duke vs. Louisville Simulated 10K Times

Duke vs. Louisville Odds

We have researched the best betting odds in America for this game, which are listed here:

  • Spread: Louisville -4 (-110), Duke +4 (-110)
  • Moneyline: Louisville -192, Duke +162
  • Total: Over/Under 47 (-110/-110)

Odds are correct at the time of publication and subject to change.

Louisville is listed as the -4 favorite against Duke, with -110 at PointsBet the best odds currently available.

For the underdog Duke (+4) to cover the spread, PointsBet also has the best odds currently on offer at -110.

  
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By Dimers